Modulation of solubility and development of a formulation of Plumbagin using hydrotropic solubilization technique

The present work aimed to increase the solubility of poorly water-soluble drug plumbagin using hydrotropic solubilization technique. Plumbagin is a potent natural product extracted from plant Plumbago zeylanica L. belonging family Plumbaginacea. It can be used treat rheumatoid arthritis, dysmenorrhea, injury, and cancer. An oral liquid syrup was prepared caffeine as agent. results showed 97 folds in when Moreover, various evaluation tests like pH, refractive index determination, content developed were performed. All satisfactory outcomes proved that it possible create stable dosage form